A case of possible drug-induced liver injury due to COVID-19 vaccine.

The patient presented with nausea, appetite loss, and fatigue. She had received two doses of Pfizer/BioN-Tech BNT162b2 mRNA vaccine (COMIRNATY) for coronavirus disease 2019 (COVID-19). Acute liver injury was noted 14 days after the first dose of the vaccine. Re-exposure through the second dose worsened the liver injury. After liver biopsy on the third day of admission, methylprednisolone (1000 mg) was administered. Liver histology showed acute hepatitis with diffuse lobular inflammation/necrosis and lymphocyte-dominant infiltra-tion in the portal areas. The patient was diagnosed with drug-induced liver injury due to the COVID-19 vaccine based on the Digestive Disease Week Japan 2004 (DDW-J) scale, which assesses the temporal relationship, liver biopsy, and laboratory findings. With improvements in the blood test parameters, prednisolone was gradually tapered and stopped. One month later, no biochemical signs of relapse were noted. To our knowledge, this is the first report describing liver injury after the administration of the Pfizer COVID-19 vaccine in Japan.Copyright © 2022 The Japan Society of Hepatology.

Comparison Analysis of E-waste Management in India and Japan: Challenges and Solutions with a Focus on the COVID-19 Pandemic

E-waste termed as Waste Electronic and Electrical Equipment (WEEE) is managed under the laws of many countries including India and Japan. India and Japan are proceeding with discussions on challenges and opportunities to improve their respective e-waste management. Based on the latest information surveys and field studies, this study aims to serve as a valuable input for decision-making processes to change risks under COVID-19 to opportunities. Regulations and circumstances of e-waste management, Occupational Safety and Health (OSH), and effects and correspondences to the COVID-19 pandemic in India and Japan were explored. From the results obtained, solutions to improve e-waste management and OSH under COVID-19 were argued on and suggested to both countries. The contribution of this study is to include the COVID-19 related issues and challenges in the previous respective e-waste management researches in India and Japan and also to suggest new solutions as recommendations. © 2023 selection and editorial matter, Biswajit Debnath, Abhijit Das, Potluri Anil Chowdary, and Siddhartha Bhattacharyya;individual chapters, the contributors.

A case of possible drug-induced liver injury due to COVID-19 vaccine

The patient presented with nausea, appetite loss, and fatigue. She had received two doses of Pfizer/BioN-Tech BNT162b2 mRNA vaccine (COMIRNATYR) for coronavirus disease 2019 (COVID-19). Acute liver injury was noted 14 days after the first dose of the vaccine. Re-exposure through the second dose worsened the liver injury. After liver biopsy on the third day of admission, methylprednisolone (1000 mg) was administered. Liver histology showed acute hepatitis with diffuse lobular inflammation/necrosis and lymphocyte-dominant infiltra-tion in the portal areas. The patient was diagnosed with drug-induced liver injury due to the COVID-19 vaccine based on the Digestive Disease Week Japan 2004 (DDW-J) scale, which assesses the temporal relationship, liver biopsy, and laboratory findings. With improvements in the blood test parameters, prednisolone was gradually tapered and stopped. One month later, no biochemical signs of relapse were noted. To our knowledge, this is the first report describing liver injury after the administration of the Pfizer COVID-19 vaccine in Japan. Copyright © 2022 The Japan Society of Hepatology.

COVID-19 and fiscal stimulus in South Asia: implications for resilience and sustainable development

The world continues to be gripped by COVID-19, though the pandemic's impact varies across countries and regions. The South Asian case is illustrative. The region is marked by inherent socioeconomic and other vulnerabilities, including high population density, relatively poor health care, and limited water sanitation facilities. South Asian countries also evince varied levels of damage from the pandemic. This chapter examines the region's circumstances as of November 2020, using macroeconomic data to explore varied pandemic impacts and fiscal policy responses. We also discuss the COVID-19 fund formed at the South Asian regional level with contributions from all eight South Asian countries. Our analysis includes each country's external and internal share of fiscal stimulus, and the implications for sustainable development goals. In an argument for integrating resilience and development frameworks, the chapter analyzes Japan's example of national resilience planning and related sustainable development frameworks. Our research indicates that a sustainable recovery is advantaged by fiscal stimulus that can be linked to extant developmental frameworks. © 2022 Elsevier Inc. All rights reserved.

Remote medical education in Indonesia: analysis of 10 years of activities

Introduction: With ongoing development of technology, and especially amid the current COVID-19 pandemic, there is rapidly increasing need for remote communications, including in the field of medical education. This study aimed to evaluate our telemedicine activities between Japan and Indonesia.